Mevastatin

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Selleck Chemicals

S4223-50MG

€144,00 EUR
€144,00 EUR
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Mevastatin is an inhibitor of HMG-CoA Reductase used in studies of Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to metabolic regulation, energy sensing, and enzyme-linked homeostasis in cardiovascular and metabolism models.

By inhibiting HMG-CoA Reductase, Mevastatin can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cardiovascular and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HMG-CoA Reductase
  • Pathway perturbation studies connected to Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Mevastatin is appropriate when a defined chemical perturbant is needed to connect HMG-CoA Reductase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HMG-CoA Reductase
Target Class:
Enzyme
Pathways:
Metabolic Signaling
Research Area:
Cardiovascular • Metabolism
CAS No.:
73573-88-3
Molecular Weight:
390.51
Formula:
C₂₃H₃₄O₅
SMILES:
CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O
InChIKey:
BOZILQFLQYBIIY-INTXDZFKSA-N
PubChem:
64715
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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