Milnacipran HCl
Selleck Chemicals
SKU:S3140-10MG
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Milnacipran HCl is an inhibitor of Serotonin Transporter and Norepinephrine Transporter used in studies of Neurotransmission. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.
By inhibiting Serotonin Transporter and Norepinephrine Transporter, Milnacipran HCl can be used to examine synaptic signaling, receptor activity, and neuronal excitability. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Serotonin Transporter and Norepinephrine Transporter
- Pathway perturbation studies connected to Neurotransmission
- Concentration-response inhibition and target-dependence studies
- Transport, uptake/efflux, and permeability assays
Overall, Milnacipran HCl is appropriate when a defined chemical perturbant is needed to connect Serotonin Transporter and Norepinephrine Transporter with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Serotonin Transporter • Norepinephrine Transporter
- Target Class:
- Transporter
- Pathways:
- Neurotransmission
- Research Area:
- Neuroscience
- CAS No.:
- 101152-94-7
- Molecular Weight:
- 282.81
- Formula:
- C₁₅H₂₂N₂O·HCl
- SMILES:
- CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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