Mizagliflozin (KWA 0711, DSP-3235 free base)

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Selleck Chemicals

S8939-5MG

€265,00 EUR
€265,00 EUR
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Mizagliflozin (KWA 0711, DSP-3235 free base) is an inhibitor of SGLT1 and SGLT used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By inhibiting SGLT1 and SGLT, Mizagliflozin (KWA 0711, DSP-3235 free base) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT1 and SGLT
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Mizagliflozin (KWA 0711, DSP-3235 free base) is appropriate when a defined chemical perturbant is needed to connect SGLT1 and SGLT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT1 • SGLT
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
666843-10-3
Molecular Weight:
564.67
Formula:
C₂₈H₄₄N₄O₈
SMILES:
CC1=C(C=CC(=C1)OCCCNCC(C)(C)C(=O)N)CC2=C(NN=C2OC3C(C(C(C(O3)CO)O)O)O)C(C)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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