Mizoribine
Selleck Chemicals
SKU:S1384-10MG
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Mizoribine is an inhibitor of DNA/RNA Synthesis used in studies of DNA Damage Response and Viral Entry / Replication and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and host-pathogen interactions, entry mechanisms, and replication-associated responses in cancer, dna damage / repair, and infectious disease models.
By inhibiting DNA/RNA Synthesis, Mizoribine can be used to examine checkpoint activation, DNA repair, and genome-stability control and host-pathogen interactions, entry mechanisms, and replication-associated responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving DNA/RNA Synthesis
- Pathway perturbation studies connected to DNA Damage Response and Viral Entry / Replication and related signaling programs
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, Mizoribine is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- DNA/RNA Synthesis
- Target Class:
- Enzyme
- Pathways:
- DNA Damage Response • Viral Entry / Replication • Metabolic Signaling
- Research Area:
- Cancer • DNA Damage / Repair • Infectious Disease
- CAS No.:
- 50924-49-7
- Molecular Weight:
- 259.22
- Formula:
- C₉H₁₃N₃O₆
- SMILES:
- C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N
- InChIKey:
- HZQDCMWJEBCWBR-UHFFFAOYSA-N
- PubChem:
- 104762
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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