ML277

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Selleck Chemicals

S0050-5MG

€301,00 EUR
€301,00 EUR
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ML277 is an activator of Potassium Channels used in studies of ion-channel pharmacology. In practice, this places the compound in experiments that measure ion conductance, membrane potential, and electrophysiological responses in cardiovascular and neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By activating Potassium Channels, ML277 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Potassium Channels
  • Gain-of-function pathway-activation studies
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cardiovascular and neuroscience models

Overall, ML277 is appropriate when a defined chemical perturbant is needed to connect Potassium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Potassium Channels
Target Class:
Ion Channel
Research Area:
Cardiovascular • Neuroscience
CAS No.:
1401242-74-7
Molecular Weight:
471.59
Formula:
C₂₃H₂₅N₃O₄S₂
SMILES:
CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C(=O)NC3=NC(=CS3)C4=CC=C(C=C4)OC
InChIKey:
OXQNLLVUVDAEHC-UHFFFAOYSA-N
PubChem:
53347902
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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