ML385

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Selleck Chemicals

S8790-5MG

€144,00 EUR
€144,00 EUR
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ML385 is an inhibitor of NRF2 used in studies of Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses in immunology, inflammation, and metabolism models.

By inhibiting NRF2, ML385 can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NRF2
  • Pathway perturbation studies connected to Oxidative Stress Response
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, ML385 is appropriate when a defined chemical perturbant is needed to connect NRF2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NRF2
Target Class:
Signaling Pathway Modulator
Pathways:
Oxidative Stress Response
Research Area:
Immunology • Inflammation • Metabolism • Oxidative Stress
CAS No.:
846557-71-9
Molecular Weight:
511.59
Formula:
C₂₉H₂₅N₃O₄S
SMILES:
CC1=CC=CC=C1C(=O)N2CCC3=C2C=CC(=C3)C4=C(SC(=N4)NC(=O)CC5=CC6=C(C=C5)OCO6)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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