Molibresib (I-BET-762)
Selleck Chemicals
SKU:S7189-2MG
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Molibresib (I-BET-762) is an inhibitor of BET used in studies of Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to chromatin-state control, histone modification, and transcriptional regulation in cancer, epigenetics, and immunology models.
By inhibiting BET, Molibresib (I-BET-762) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, epigenetics, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving BET
- Pathway perturbation studies connected to Epigenetic Regulation
- Concentration-response inhibition and target-dependence studies
- Chromatin, epigenetic, and gene-expression profiling
Overall, Molibresib (I-BET-762) is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, epigenetics, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- BET
- Target Class:
- Epigenetic Regulator
- Pathways:
- Epigenetic Regulation
- Research Area:
- Cancer • Epigenetics • Immunology • Inflammation
- CAS No.:
- 1260907-17-2
- Molecular Weight:
- 423.9
- Formula:
- C₂₂H₂₂ClN₅O₂
- SMILES:
- CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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