MRX-2843

1 1

Selleck Chemicals

S6839-5MG

€392,00 EUR
€392,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

MRX-2843 is an inhibitor of FLT3 used in studies of MAPK / ERK Signaling and JAK-STAT Signaling. It is especially relevant in cancer and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation.

By inhibiting FLT3, MRX-2843 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving FLT3
  • Pathway perturbation studies connected to MAPK / ERK Signaling and JAK-STAT Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, MRX-2843 is appropriate when a defined chemical perturbant is needed to connect FLT3 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
FLT3
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • JAK-STAT Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
1429882-07-4
Molecular Weight:
488.67
Formula:
C₂₉H₄₀N₆O
SMILES:
CN1CCN(CC1)CC2=CC=C(C=C2)C3=C[N](C4CCC(O)CC4)C5=NC(=NC=C35)NCCC6CC6
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.