Myosin IE (MYO1E or FSGS6) Antibody

Biological Background

To connect mechanism with measurement, this antibody lets you explore Myosin IE in pathway-driven studies. Myosin IE is a structural protein that interfaces with actin, microtubules, or associated adaptors. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

In some datasets and protocols, it is referenced by the gene symbol MYO1E.

Use in the Laboratory

Because cytoskeletal proteins can be abundant, interpretation benefits from attention to dynamic range and saturation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.

Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.

To keep datasets interpretable, labs often document:

• differences across cell density or substrate stiffness
• association with junctional complexes or focal adhesions
• stress-fiber versus cortical distribution patterns

Version Notes

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.

If your study spans multiple model systems, it can help to define a shared reference condition for Myosin IE so cross-sample contrasts stay meaningful.

The regular format option supports mechanistic reading of Myosin IE when interactions and context are the focus.