Myosin IE (MYO1E or FSGS6) Antibody - FFPE Validated
BiCell Scientific
SKU:30101-FFPE-50UL
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About the Target
Bring Myosin IE (MYO1E) into view to evaluate changes across conditions. Myosin IE is a scaffold that can coordinate signaling with cytoskeletal remodeling. Focus on trends across conditions rather than single-point snapshots.
Monitoring Myosin IE alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Cytoskeletal targets are often examined during migration, adhesion changes, and responses to mechanical cues. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.
Consider these angles when interpreting target-level changes:
- association with junctional complexes or focal adhesions
- remodeling after perturbation of polymerization or contractility
- differences across cell density or substrate stiffness
- stress-fiber versus cortical distribution patterns
Variant Considerations
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Myosin IE, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting Myosin IE, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
With a clear focus on Myosin IE (MYO1E), this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- MYO1E
- Research Area:
- Cell Signaling
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of human Myosin IE protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q12965
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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