N-cadherin (Cdh2 or CD325) Antibody
BiCell Scientific
SKU:00102-50UL
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Protein Function
This antibody is suited for researchers who want to analyze N-cadherin and relate it to cell-state biology. N-cadherin is a contact-site protein that shapes barrier properties and signaling at the cell surface. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CD325.
Experimental Applications
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Common experimental questions that benefit from target tracking include:
- subcellular redistribution at contact sites versus cytoplasm
- comparative profiling across cell states or perturbations
- co-localization patterns with cytoskeletal elements
Workflow Perspective
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
If your study spans multiple model systems, it can help to define a shared reference condition for N-cadherin so cross-sample contrasts stay meaningful.
As you refine hypotheses around N-cadherin, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- CDH2
- Research Area:
- Developmental Biology • Immunology • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human N-cadherin protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P19022
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence (this sequence has no homology to other cadherin isoforms)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C