Nafamostat mesilate (FUT-175)

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Selleck Chemicals

S1386-10MG

€144,00 EUR
€144,00 EUR
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Nafamostat mesilate (FUT-175) is an inhibitor of Serine Proteases used in studies of Apoptosis and Viral Entry / Replication. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and host-pathogen interactions, entry mechanisms, and replication-associated responses in apoptosis, cancer, and immunology models.

By inhibiting Serine Proteases, Nafamostat mesilate (FUT-175) can be used to examine caspase-associated cell-death signaling and survival decisions and host-pathogen interactions, entry mechanisms, and replication-associated responses. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Serine Proteases
  • Pathway perturbation studies connected to Apoptosis and Viral Entry / Replication
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays

Overall, Nafamostat mesilate (FUT-175) is appropriate when a defined chemical perturbant is needed to connect Serine Proteases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Serine Proteases
Target Class:
Protease
Pathways:
Apoptosis • Viral Entry / Replication
Research Area:
Apoptosis • Cancer • Immunology • Inflammation
CAS No.:
82956-11-4
Molecular Weight:
539.58
Formula:
C₁₉H₁₇N₅O₂·2CH₄O₃S
SMILES:
CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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