Namodenoson (CF-102)

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Selleck Chemicals

SKU:S0498-5MG

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Namodenoson (CF-102) is an agonist of Adenosine Receptors used in studies of PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling in cardiovascular, developmental biology, and immunology models.

By activating Adenosine Receptors, Namodenoson (CF-102) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular, developmental biology, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Adenosine Receptors
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Namodenoson (CF-102) is appropriate when a defined chemical perturbant is needed to connect Adenosine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, developmental biology, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Adenosine Receptors
Target Class:
GPCR
Pathways:
PI3K-Akt-mTOR Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Cardiovascular • Developmental Biology • Immunology • Inflammation
CAS No.:
163042-96-4
Molecular Weight:
544.73
Formula:
C₁₈H₁₈ClIN₆O₄
SMILES:
CNC(=O)C1C(C(C(O1)N2C=NC3=C(N=C(N=C32)Cl)NCC4=CC(=CC=C4)I)O)O
InChIKey:
IPSYPUKKXMNCNQ-UHFFFAOYSA-N
PubChem:
3035850
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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