NDCBE (Slc4a8) Antibody - FFPE Validated
BiCell Scientific
SKU:20502-FFPE-50UL
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About the Target
Plan your comparisons around NDCBE (Slc4a8) and use this antibody to evaluate state-dependent differences. NDCBE is a membrane-embedded regulator of ionic or osmotic balance in cells. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol Slc4a8.
Research Context
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Time course design can be decisive when regulation is transient or compartment dependent.
Consider these angles when interpreting target-level changes:
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
Variant Considerations
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so NDCBE patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so NDCBE patterns can be compared across experiments without guesswork.
Integrate the fixed-section version into your design so NDCBE (Slc4a8) signals can be interpreted alongside matched controls.
- Targets:
- SLC4A8
- Research Area:
- Metabolism
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (19-aa) derived from the C-terminal region of mouse NDCBE protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q2Y0W8
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.2% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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