Nelfinavir

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Selleck Chemicals

SKU:S9626-5MG

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Nelfinavir is an inhibitor of Autophagy and HIV Protease used in studies of Apoptosis and Autophagy and related signaling programs. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation.

By inhibiting Autophagy and HIV Protease, Nelfinavir can be used to examine caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation. The autophagy modulator annotation adds relevance to autophagy-flux and lysosomal-response studies, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Autophagy and HIV Protease
  • Pathway perturbation studies connected to Apoptosis and Autophagy and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Autophagy-flux and lysosomal-response studies

Overall, Nelfinavir is appropriate when a defined chemical perturbant is needed to connect Autophagy and HIV Protease with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Autophagy • HIV Protease
Target Class:
Autophagy Modulator
Pathways:
Apoptosis • Autophagy • Viral Entry / Replication
Research Area:
Apoptosis • Autophagy • Cancer • Infectious Disease
CAS No.:
159989-64-7
Molecular Weight:
567.78
Formula:
C₃₂H₄₅N₃O₄S
SMILES:
Cc1c(O)cccc1C(O)=N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(O)=NC(C)(C)C
InChIKey:
QAGYKUNXZHXKMR-HKWSIXNMSA-N
PubChem:
64143
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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