NHE2 (Slc9a2) Antibody
BiCell Scientific
SKU:21002-50UL
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Scientific Overview
For consistent comparison across experiments, use this antibody to analyze NHE2 (Slc9a2) with a repeatable workflow. NHE2 is a membrane-embedded regulator of ionic or osmotic balance in cells. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol Slc9a2.
Research Relevance
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
When interpreting NHE2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Pair this regular format format with stable controls to keep NHE2 (Slc9a2) measurements coherent over time.
- Targets:
- SLC9A2
- Research Area:
- Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of mouse NHE2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UBY0
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 75% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C