Nimodipine

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Selleck Chemicals

SKU:S1747-50MG

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Nimodipine is an inhibitor of Calcium Channels and Autophagy used in studies of Autophagy and Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to autophagic flux, lysosomal turnover, and stress adaptation and calcium flux, excitability, and secretion-linked signaling in autophagy, cardiovascular, and cell signaling models.

By inhibiting Calcium Channels and Autophagy, Nimodipine can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In autophagy, cardiovascular, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Calcium Channels and Autophagy
  • Pathway perturbation studies connected to Autophagy and Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Nimodipine is appropriate when a defined chemical perturbant is needed to connect Calcium Channels and Autophagy with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cardiovascular, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Calcium Channels • Autophagy
Target Class:
Ion Channel
Pathways:
Autophagy • Calcium Signaling
Research Area:
Autophagy • Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
66085-59-4
Molecular Weight:
418.44
Formula:
C₂₁H₂₆N₂O₇
SMILES:
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
InChIKey:
UIAGMCDKSXEBJQ-UHFFFAOYSA-N
PubChem:
4497
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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