NKL 22
Selleck Chemicals
SKU:S6548-5MG
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NKL 22 is an inhibitor of HDAC used in studies of Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.
By inhibiting HDAC, NKL 22 can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving HDAC
- Pathway perturbation studies connected to Epigenetic Regulation
- Concentration-response inhibition and target-dependence studies
- Chromatin, epigenetic, and gene-expression profiling
Overall, NKL 22 is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- HDAC
- Target Class:
- Epigenetic Regulator
- Pathways:
- Epigenetic Regulation
- Research Area:
- Cancer • Epigenetics
- CAS No.:
- 537034-15-4
- Molecular Weight:
- 325.40
- Formula:
- C₁₉H₂₃N₃O₂
- SMILES:
- C1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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