Novobiocin Sodium (Cathomycin, Albamycin)
Selleck Chemicals
SKU:S2492-50MG
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Novobiocin Sodium (Cathomycin, Albamycin) is an inhibitor of HSP90 and Topoisomerase used in studies of DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control in cancer, dna damage / repair, and infectious disease models.
By inhibiting HSP90 and Topoisomerase, Novobiocin Sodium (Cathomycin, Albamycin) can be used to examine checkpoint activation, DNA repair, and genome-stability control. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, dna damage / repair, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving HSP90 and Topoisomerase
- Pathway perturbation studies connected to DNA Damage Response
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in cancer, dna damage / repair, and infectious disease models
Overall, Novobiocin Sodium (Cathomycin, Albamycin) is appropriate when a defined chemical perturbant is needed to connect HSP90 and Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- HSP90 • Topoisomerase
- Target Class:
- Other
- Pathways:
- DNA Damage Response
- Research Area:
- Cancer • DNA Damage / Repair • Infectious Disease • Metabolism
- CAS No.:
- 1476-53-5
- Molecular Weight:
- 634.61
- Formula:
- C₃₁H₃₅N₂O₁₁·Na
- SMILES:
- CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)[O-])CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O.[Na+]
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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