NS1652

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Selleck Chemicals

S2955-25MG

€883,00 EUR
€883,00 EUR
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NS1652 is an inhibitor of VRAC used in studies of ion-channel pharmacology. In practice, this places the compound in experiments that measure ion conductance, membrane potential, and electrophysiological responses in cell signaling models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting VRAC, NS1652 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving VRAC
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cell signaling models

Overall, NS1652 is appropriate when a defined chemical perturbant is needed to connect VRAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
VRAC
Target Class:
Ion Channel
Research Area:
Cell Signaling
CAS No.:
1566-81-0
Molecular Weight:
324.25
Formula:
C₁₅H₁₁F₃N₂O₃
SMILES:
OC(=O)C1=CC=CC=C1NC(=O)NC2=CC=CC(=C2)C(F)(F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.