NVS-PAK1-1
Selleck Chemicals
SKU:S8264-5MG
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NVS-PAK1-1 is an inhibitor of PAK1 used in studies of MAPK / ERK Signaling. It is especially relevant in cancer, cell cycle, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.
By inhibiting PAK1, NVS-PAK1-1 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving PAK1
- Pathway perturbation studies connected to MAPK / ERK Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, NVS-PAK1-1 is appropriate when a defined chemical perturbant is needed to connect PAK1 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- PAK1
- Target Class:
- Kinase
- Pathways:
- MAPK / ERK Signaling
- Research Area:
- Cancer • Cell Cycle • Cell Signaling
- CAS No.:
- 1783816-74-9
- Molecular Weight:
- 479.93
- Formula:
- C₂₃H₂₅ClF₃N₅O
- SMILES:
- CC(C)NC(=O)N1CCC(C1)NC2=NC3=CC(=CC=C3N(CC(F)F)C4=C2C=C(Cl)C=C4)F
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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