Obacunone (AI3-37934)
Selleck Chemicals
SKU:S3784-5MG
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Obacunone (AI3-37934) is an inhibitor of NRF2 used in studies of Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses in endocrinology, inflammation, and oxidative stress models.
By inhibiting NRF2, Obacunone (AI3-37934) can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In endocrinology, inflammation, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving NRF2
- Pathway perturbation studies connected to Oxidative Stress Response
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, Obacunone (AI3-37934) is appropriate when a defined chemical perturbant is needed to connect NRF2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, inflammation, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- NRF2
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- Oxidative Stress Response
- Research Area:
- Endocrinology • Inflammation • Oxidative Stress
- CAS No.:
- 751-03-1
- Molecular Weight:
- 454.51
- Formula:
- C₂₆H₃₀O₇
- SMILES:
- CC1(C2CC(=O)C3(C(C2(C=CC(=O)O1)C)CCC4(C35C(O5)C(=O)OC4C6=COC=C6)C)C)C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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