OC000459

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Selleck Chemicals

S2822-5MG

€265,00 EUR
€265,00 EUR
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OC000459 is an antagonist of GPR used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cell signaling and endocrinology models.

By blocking GPR, OC000459 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cell signaling and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GPR
  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, OC000459 is appropriate when a defined chemical perturbant is needed to connect GPR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GPR
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cell Signaling • Endocrinology
CAS No.:
851723-84-7
Molecular Weight:
348.37
Formula:
C₂₁H₁₇FN₂O₂
SMILES:
CC1=C(C2=C(N1CC(=O)O)C=CC(=C2)F)CC3=NC4=CC=CC=C4C=C3
InChIKey:
FATGTHLOZSXOBC-UHFFFAOYSA-N
PubChem:
11462174
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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