Occludin (Ocln) (C-Terminus) Antibody - FFPE Validated
BiCell Scientific
SKU:00241-FFPE-50UL
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About the Target
This antibody enables you to characterize Occludin C-Terminus (Ocln) with a direct, biology-first readout. Occludin C-Terminus is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Focus on trends across conditions rather than single-point snapshots.
In some datasets and protocols, it is referenced by the gene symbol Ocln.
Research Context
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Consider these angles when interpreting target-level changes:
- co-localization patterns with cytoskeletal elements
- subcellular redistribution at contact sites versus cytoplasm
- changes in complex assembly with scaffold or adaptor proteins
- comparative profiling across cell states or perturbations
Variant Considerations
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Occludin C-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting Occludin C-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Select the fixed-section version to keep Occludin C-Terminus (Ocln) interpretation aligned with your workflow goals.
- Targets:
- OCLN
- Research Area:
- Developmental Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal intracellular region of human occludin protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16625
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C