Occludin (Ocln) (N-Terminus) Antibody

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BiCell Scientific

SKU:00241N-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

When control selection matters, this antibody helps you evaluate Occludin N-Terminus (Ocln) in a structured study. Occludin N-Terminus is a membrane-associated component that helps organize cell-cell contacts and polarity. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.

In some datasets and protocols, it is referenced by the gene symbol Ocln.

Research Relevance

In cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Time course design can be decisive when regulation is transient or compartment dependent.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

  • comparative profiling across cell states or perturbations
  • subcellular redistribution at contact sites versus cytoplasm
  • changes in complex assembly with scaffold or adaptor proteins

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. Align controls to the expected direction of change to support confident interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for Occludin N-Terminus so cross-sample contrasts stay meaningful.

Use the regular format option to keep Occludin N-Terminus (Ocln) analysis aligned with planned contrasts and endpoints.

Targets:
OCLN
Research Area:
Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (17-aa) derived from the N-terminal intracellular region of mouse occludin protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q16625
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 88.2% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C