Oleandrin (PBI-05204)

1 1

Selleck Chemicals

S6918-5MG

€431,00 EUR
€431,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Oleandrin (PBI-05204) is an inhibitor of ATPases used in studies of Apoptosis. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell signaling models.

By inhibiting ATPases, Oleandrin (PBI-05204) can be used to examine caspase-associated cell-death signaling and survival decisions. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ATPases
  • Pathway perturbation studies connected to Apoptosis
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Oleandrin (PBI-05204) is appropriate when a defined chemical perturbant is needed to connect ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ATPases
Target Class:
Enzyme
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Cell Signaling
CAS No.:
465-16-7
Molecular Weight:
576.72
Formula:
C₃₂H₄₈O₉
SMILES:
COC1CC(OC(C)C1O)OC2CCC3(C)C(CCC4C3CCC5(C)C(C(CC45O)OC(C)=O)C6=CC(=O)OC6)C2
InChIKey:
JLPDBLFIVFSOCC-UHFFFAOYSA-N
PubChem:
11541511
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.