Olopatadine HCl

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Selleck Chemicals

SKU:S2494-10MG

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Olopatadine HCl is an inhibitor of Histamine Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in inflammation and neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.

By inhibiting Histamine Receptors, Olopatadine HCl can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Histamine Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Olopatadine HCl is appropriate when a defined chemical perturbant is needed to connect Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Histamine Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Inflammation • Neuroscience
CAS No.:
140462-76-6
Molecular Weight:
373.87
Formula:
C₂₁H₂₃NO₃·HCl
SMILES:
CN(C)CCC=C1C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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