Omecamtiv mecarbil (CK-1827452)
Selleck Chemicals
SKU:S2623-5MG
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Omecamtiv mecarbil (CK-1827452) is an activator of ATPases used in studies of enzyme regulation. It is especially relevant in cell signaling models, where defined compound exposure can be linked to catalytic activity, substrate turnover, and enzymatic regulation.
By activating ATPases, Omecamtiv mecarbil (CK-1827452) can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving ATPases
- Gain-of-function pathway-activation studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
- Phenotypic profiling in cell signaling models
Overall, Omecamtiv mecarbil (CK-1827452) is appropriate when a defined chemical perturbant is needed to connect ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- ATPases
- Target Class:
- Enzyme
- Research Area:
- Cell Signaling
- CAS No.:
- 873697-71-3
- Molecular Weight:
- 401.43
- Formula:
- C₂₀H₂₄FN₅O₃
- SMILES:
- CC1=NC=C(C=C1)NC(=O)NC2=CC=CC(=C2F)CN3CCN(CC3)C(=O)OC
- InChIKey:
- RFUBTTPMWSKEIW-UHFFFAOYSA-N
- PubChem:
- 11689883
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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