Opaganib (ABC294640)

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Selleck Chemicals

S7174-5MG

€144,00 EUR
€144,00 EUR
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Opaganib (ABC294640) is an inhibitor of SK2 used in studies of Metabolic Signaling. In practice, this places the compound in experiments that measure metabolic regulation, energy sensing, and enzyme-linked homeostasis in cancer, cell signaling, and immunology models.

By inhibiting SK2, Opaganib (ABC294640) can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SK2
  • Pathway perturbation studies connected to Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Opaganib (ABC294640) is appropriate when a defined chemical perturbant is needed to connect SK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SK2
Target Class:
Kinase
Pathways:
Metabolic Signaling
Research Area:
Cancer • Cell Signaling • Immunology • Inflammation
CAS No.:
915385-81-8
Molecular Weight:
380.91
Formula:
C₂₃H₂₅ClN₂O
SMILES:
C1C2CC3(CC1CC(C2)(C3)C(=O)NCC4=CC=NC=C4)C5=CC=C(C=C5)Cl
InChIKey:
CAOTVXGYTWCKQE-UHFFFAOYSA-N
PubChem:
15604015
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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