Orphenadrine Hydrochloride
Selleck Chemicals
SKU:S5664-25MG
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Orphenadrine Hydrochloride is an antagonist of NMDAR used in studies of Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling in neuroscience models.
By blocking NMDAR, Orphenadrine Hydrochloride can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving NMDAR
- Pathway perturbation studies connected to Calcium Signaling
- Receptor-blockade and ligand-competition studies
- Electrophysiology, ion-flux, and membrane-potential studies
Overall, Orphenadrine Hydrochloride is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- NMDAR
- Target Class:
- Ion Channel
- Pathways:
- Calcium Signaling
- Research Area:
- Neuroscience
- CAS No.:
- 341-69-5
- Molecular Weight:
- 305.84
- Formula:
- C₁₈H₂₄ClNO
- SMILES:
- CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.Cl
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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