P2RX7 (P2X7) Antibody

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BiCell Scientific

SKU:15167-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody helps you characterize P2RX7 (P2X7) while keeping condition-to-condition contrasts straightforward. P2RX7 is a channel or transporter associated with regulated flux across cellular membranes. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.

Following P2RX7 across perturbations can help separate expression effects from compartment shifts.

Research Context

Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

Consider these angles when interpreting target-level changes:

  • relative abundance across engineered constructs
  • patterns consistent with apical or basolateral sorting
  • surface versus intracellular pool distribution
  • stimulus-dependent trafficking and turnover

Variant Considerations

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so P2RX7 patterns can be compared across experiments without guesswork.

When interpreting P2RX7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

With consistent handling, the regular format format can make P2RX7 (P2X7) comparisons easier to reproduce across runs.

Targets:
P2RX7
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse P2RX7 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q99572
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 92.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C