Paeoniflorin (NSC 178886)

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Selleck Chemicals

S2410-25MG

€108,00 EUR
€108,00 EUR
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Paeoniflorin (NSC 178886) is an inhibitor of COX used in studies of PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling in immunology and inflammation models.

By inhibiting COX, Paeoniflorin (NSC 178886) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving COX
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Paeoniflorin (NSC 178886) is appropriate when a defined chemical perturbant is needed to connect COX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
COX
Target Class:
Enzyme
Pathways:
PI3K-Akt-mTOR Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
23180-57-6
Molecular Weight:
480.46
Formula:
C₂₃H₂₈O₁₁
SMILES:
CC12CC3(C4CC1(C4(C(O2)O3)COC(=O)C5=CC=CC=C5)OC6C(C(C(C(O6)CO)O)O)O)O
InChIKey:
YKRGDOXKVOZESV-UHFFFAOYSA-N
PubChem:
53384387
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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