Pannexin-1 (PANX1) Antibody
BiCell Scientific
SKU:00501-50UL
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Protein Function
Build reproducible readouts by using this antibody to evaluate Pannexin-1 across matched sample sets. Pannexin-1 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol PANX1.
Experimental Applications
In cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- subcellular redistribution at contact sites versus cytoplasm
- changes in complex assembly with scaffold or adaptor proteins
- co-localization patterns with cytoskeletal elements
- comparative profiling across cell states or perturbations
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Pannexin-1 so cross-sample contrasts stay meaningful.
For multi-run studies, the regular format option helps keep Pannexin-1 trends comparable from experiment to experiment.
- Targets:
- PANX1
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal cytoplasmic region of mouse Pannexin-1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q96RD7
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)Conjugate: Unconjugated
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C