Parsaclisib (INCB050465)

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Selleck Chemicals

E0121-5MG

€579,00 EUR
€579,00 EUR
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Parsaclisib (INCB050465) is an inhibitor of PI3K delta used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant in cancer, cell signaling, and immunology models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs.

By inhibiting PI3K delta, Parsaclisib (INCB050465) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PI3K delta
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Parsaclisib (INCB050465) is appropriate when a defined chemical perturbant is needed to connect PI3K delta with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PI3K delta
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling
Research Area:
Cancer • Cell Signaling • Immunology
CAS No.:
1426698-88-5
Molecular Weight:
432.88
Formula:
C₂₀H₂₂ClFN₆O₂
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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