PD0325901 (Mirdametinib)

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Selleck Chemicals

S1036-5MG

€144,00 EUR
€144,00 EUR
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PD0325901 (Mirdametinib) is an inhibitor of MEK and ERK1 and related targets used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.

By inhibiting MEK and ERK1 and related targets, PD0325901 (Mirdametinib) can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MEK and ERK1 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, PD0325901 (Mirdametinib) is appropriate when a defined chemical perturbant is needed to connect MEK and ERK1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MEK • ERK1 • ERK2
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
391210-10-9
Molecular Weight:
482.19
Formula:
C₁₆H₁₄F₃IN₂O₄
SMILES:
C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
InChIKey:
SUDAHWBOROXANE-SECBINFHSA-N
PubChem:
9826528
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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