PDGFRA (CD140a) Antibody

Biological Background

This antibody supports experimental designs that characterize PDGFRA with interpretable controls and clear contrasts. PDGFRA is a signaling protein that can relay information through phosphorylation and complex assembly. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.

In some datasets and protocols, it is referenced by the gene symbol CD140a.

Use in the Laboratory

Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Time course design can be decisive when regulation is transient or compartment dependent. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.

To keep datasets interpretable, labs often document:

• time-resolved changes following stimulation or inhibition
• condition-to-condition comparisons with matched controls
• localization shifts between cytoplasm, membrane, and nucleus

Version Notes

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Predefine decision rules for excluding outliers so analysis remains transparent.

If your study spans multiple model systems, it can help to define a shared reference condition for PDGFRA so cross-sample contrasts stay meaningful.

Use the regular format option to keep PDGFRA analysis aligned with planned contrasts and endpoints.