PDGFRB (CD140b) Antibody
BiCell Scientific
SKU:52082-50UL
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Scientific Overview
Bring PDGFRB (CD140b) into view to analyze changes across conditions. PDGFRB is a signaling node often evaluated by abundance, localization, and modification-dependent states. Focus on trends across conditions rather than single-point snapshots.
In some datasets and protocols, it is referenced by the gene symbol CD140b.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- localization shifts between cytoplasm, membrane, and nucleus
- time-resolved changes following stimulation or inhibition
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing PDGFRB measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With a clear focus on PDGFRB (CD140b), this regular format option fits streamlined studies and fast iteration.
- Targets:
- PDGFRB
- Research Area:
- Cell Signaling • Immunology • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal cytoplasmic region of mouse PDGFRB protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P09619
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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