PDM-11

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Selleck Chemicals

S0155-5MG

€193,00 EUR
€193,00 EUR
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PDM-11 is an antagonist of Estrogen Receptor used in studies of Hormone Signaling. It is especially relevant in cancer, endocrinology, and metabolism models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.

By blocking Estrogen Receptor, PDM-11 can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, endocrinology, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, PDM-11 is appropriate when a defined chemical perturbant is needed to connect Estrogen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology • Metabolism
CAS No.:
1032508-03-4
Molecular Weight:
274.74
Formula:
C₁₆H₁₅ClO₂
SMILES:
COC1=CC(=CC(=C1)C=CC2=CC=C(C=C2)Cl)OC
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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