Peficitinib (ASP015K)

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Selleck Chemicals

S7650-5MG

€144,00 EUR
€144,00 EUR
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Peficitinib (ASP015K) is an inhibitor of JAK used in studies of JAK-STAT Signaling. It is especially relevant in cancer, cell signaling, and immunology models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation.

By inhibiting JAK, Peficitinib (ASP015K) can be used to examine cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving JAK
  • Pathway perturbation studies connected to JAK-STAT Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Peficitinib (ASP015K) is appropriate when a defined chemical perturbant is needed to connect JAK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
JAK
Target Class:
Kinase
Pathways:
JAK-STAT Signaling
Research Area:
Cancer • Cell Signaling • Immunology • Inflammation
CAS No.:
944118-01-8
Molecular Weight:
326.39
Formula:
C₁₈H₂₂N₄O₂
SMILES:
C1C2CC3CC(C2)(CC1C3NC4=C5C=CNC5=NC=C4C(=O)N)O
InChIKey:
DREIJXJRTLTGJC-UHFFFAOYSA-N
PubChem:
57928403
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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