Pentoxifylline

1 1

Selleck Chemicals

S4345-25MG

€95,00 EUR
€95,00 EUR
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Pentoxifylline is an inhibitor of PDE and PKA used in studies of enzyme regulation. It is especially relevant in cardiovascular, cell signaling, and immunology models, where defined compound exposure can be linked to catalytic activity, substrate turnover, and enzymatic regulation.

By inhibiting PDE and PKA, Pentoxifylline can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cardiovascular, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PDE and PKA
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
  • Phenotypic profiling in cardiovascular, cell signaling, and immunology models

Overall, Pentoxifylline is appropriate when a defined chemical perturbant is needed to connect PDE and PKA with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PDE • PKA
Target Class:
Enzyme
Research Area:
Cardiovascular • Cell Signaling • Immunology • Inflammation
CAS No.:
6493-05-6
Molecular Weight:
278.31
Formula:
C₁₃H₁₈N₄O₃
SMILES:
CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
InChIKey:
BYPFEZZEUUWMEJ-UHFFFAOYSA-N
PubChem:
4740
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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