PF-3716556

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Selleck Chemicals

S2222-10MG

€108,00 EUR
€108,00 EUR
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PF-3716556 is an inhibitor of Proton Pump and ATPases used in studies of transporter biology. In practice, this places the compound in experiments that measure substrate uptake, efflux, and membrane-transport control in cardiovascular, cell signaling, and metabolism models.

By inhibiting Proton Pump and ATPases, PF-3716556 can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake/efflux, and permeability assays, together with downstream-response mapping. In cardiovascular, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Proton Pump and ATPases
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays
  • Phenotypic profiling in cardiovascular, cell signaling, and metabolism models

Overall, PF-3716556 is appropriate when a defined chemical perturbant is needed to connect Proton Pump and ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Proton Pump • ATPases
Target Class:
Transporter
Research Area:
Cardiovascular • Cell Signaling • Metabolism
CAS No.:
928774-43-0
Molecular Weight:
394.47
Formula:
C₂₂H₂₆N₄O₃
SMILES:
CC1=C2C(CCOC2=CC=C1)NC3=CC(=CN4C3=NC(=C4)C)C(=O)N(C)CCO
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.