Phloretin (RJC 02792)

1 1

Selleck Chemicals

S2342-200MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Phloretin (RJC 02792) is an inhibitor of SGLT and SGLT1 and related targets used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting SGLT and SGLT1 and related targets, Phloretin (RJC 02792) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT and SGLT1 and related targets
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Phloretin (RJC 02792) is appropriate when a defined chemical perturbant is needed to connect SGLT and SGLT1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT • SGLT1 • SGLT2
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
60-82-2
Molecular Weight:
274.27
Formula:
C₁₅H₁₄O₅
SMILES:
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O
InChIKey:
VGEREEWJJVICBM-UHFFFAOYSA-N
PubChem:
4788
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.