Phlorizin

1 1

Selleck Chemicals

S2343-500MG

€144,00 EUR
€144,00 EUR
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Phlorizin is an inhibitor of SGLT and ATPases used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant in cell signaling, endocrinology, and metabolism models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting SGLT and ATPases, Phlorizin can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In cell signaling, endocrinology, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT and ATPases
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Phlorizin is appropriate when a defined chemical perturbant is needed to connect SGLT and ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling, endocrinology, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT • ATPases
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Cell Signaling • Endocrinology • Metabolism
CAS No.:
60-81-1
Molecular Weight:
436.41
Formula:
C₂₁H₂₄O₁₀
SMILES:
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.