PHTPP

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Selleck Chemicals

S8686-10MG

€124,00 EUR
€124,00 EUR
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PHTPP is an antagonist of Estrogen/Progesterone Receptors used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in endocrinology models.

By blocking Estrogen/Progesterone Receptors, PHTPP can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen/Progesterone Receptors
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, PHTPP is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen/Progesterone Receptors
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology
CAS No.:
805239-56-9
Molecular Weight:
423.31
Formula:
C₂₀H₁₁F₆N₃O
SMILES:
C1=CC=C(C=C1)C2=NN3C(=CC(=NC3=C2C4=CC=C(C=C4)O)C(F)(F)F)C(F)(F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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