Piezo1 (C-Terminus) Antibody
BiCell Scientific
SKU:20700C-50UL
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Biological Background
Bring Piezo1 C-Terminus into view to explore changes across conditions. Piezo1 C-Terminus is a membrane-embedded regulator of ionic or osmotic balance in cells. Look for shifts in distribution that track with phenotype changes.
Following Piezo1 C-Terminus across perturbations can help separate expression effects from compartment shifts.
Use in the Laboratory
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Interpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.
To keep datasets interpretable, labs often document:
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
Version Notes
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.
If your study spans multiple model systems, it can help to define a shared reference condition for Piezo1 C-Terminus so cross-sample contrasts stay meaningful.
When interpreting Piezo1 C-Terminus, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
With a clear focus on Piezo1 C-Terminus, this regular format option fits streamlined studies and fast iteration.
- Targets:
- PIEZO1
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal cytoplasmic region of human Piezo1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q92508
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C