Piezo1 (Internal) Antibody
BiCell Scientific
SKU:20700-50UL
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Protein Function
When control selection matters, this antibody helps you investigate Piezo1 (Internal) in a structured study. Piezo1 is a membrane-embedded regulator of ionic or osmotic balance in cells. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol Internal.
Experimental Applications
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Time course design can be decisive when regulation is transient or compartment dependent.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Workflow Perspective
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
For challenging targets, pairing Piezo1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Integrate the regular format version into your design so Piezo1 (Internal) signals can be interpreted alongside matched controls.
- Targets:
- PIEZO1
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the internal region of rat Piezo1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q92508
- Homology:
- Synthetic peptide sequence showing 85.7% homology to mouse sequence and 57.1% homology to human sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C