Piezo2 Antibody

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BiCell Scientific

SKU:20712-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody is suited for researchers who want to evaluate Piezo2 and relate it to cell-state biology. Piezo2 is a channel or transporter associated with regulated flux across cellular membranes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Tracking Piezo2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Research Context

Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Consider these angles when interpreting target-level changes:

  • relative abundance across engineered constructs
  • surface versus intracellular pool distribution
  • patterns consistent with apical or basolateral sorting

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

When interpreting Piezo2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For challenging targets, pairing Piezo2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

Use the regular format variant when your project demands Piezo2 readouts that respect preparation constraints.

Targets:
PIEZO2
Research Area:
Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of human Piezo2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q9H5I5
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C