PIK3C2B (C2-PI3K) Antibody
BiCell Scientific
SKU:52742-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you investigate PIK3C2B in pathway-driven studies. PIK3C2B is a pathway component whose activation state and localization can change after stimulation. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring PIK3C2B alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- interaction patterns within multi-protein complexes
- condition-to-condition comparisons with matched controls
- time-resolved changes following stimulation or inhibition
Variant Considerations
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for PIK3C2B so cross-sample contrasts stay meaningful.
For challenging targets, pairing PIK3C2B measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
The regular format option supports mechanistic reading of PIK3C2B when interactions and context are the focus.
- Targets:
- PIK3C2B
- Research Area:
- Cell Signaling • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse PIK3C2B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O00750
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 88.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.