PIK3C2G (PI3K-C2-gamma) Antibody - FFPE Validated

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BiCell Scientific

SKU:52743-FFPE-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

This antibody is suited for researchers who want to evaluate PIK3C2G and relate it to cell-state biology. PIK3C2G is a pathway component whose activation state and localization can change after stimulation. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Monitoring PIK3C2G alongside context markers can improve interpretation when phenotypes are subtle.

Research Relevance

When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.

When building a narrative around the target, it helps to track:

  • condition-to-condition comparisons with matched controls
  • interaction patterns within multi-protein complexes
  • localization shifts between cytoplasm, membrane, and nucleus

Application-Specific Context

In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

When interpreting PIK3C2G, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PIK3C2G patterns can be compared across experiments without guesswork.

The fixed-section version supports deeper biological narratives around PIK3C2G without overcomplicating setup.

Targets:
PIK3C2G
Research Area:
Cell Signaling • Metabolism
Application:
IHC-P
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (18-aa) derived from the C-terminal region of mouse PIK3C2G protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
O75747
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 88.9% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C