PIK3C3 Antibody - Western Blot Validated
BiCell Scientific
SKU:52751-WB-50UL
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Scientific Overview
When you need to explore PIK3C3 with attention to cellular organization, this antibody provides a focused option. PIK3C3 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring PIK3C3 alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- condition-to-condition comparisons with matched controls
- localization shifts between cytoplasm, membrane, and nucleus
- interaction patterns within multi-protein complexes
Application-Specific Context
If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for PIK3C3 so cross-sample contrasts stay meaningful.
For challenging targets, pairing PIK3C3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
As you refine hypotheses around PIK3C3, the denaturing-format format helps keep conclusions tied to preparation context.
- Targets:
- PIK3C3
- Research Area:
- Cell Signaling • Metabolism
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of human PIK3C3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8NEB9
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C